Program

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WORKSHOP “INTRODUCTION TO METAGENOMIC DATA ANALYSIS WITH bioBakery”

Plenary Hall (Amphitheatеr)

Instructors: 
Aitor Blanco-Míguez, Coordinator Microbiome Bioinformatic Core, Prebiomics, Italy
Francesco Asnicar, Tenure-track researcher, Department CIBIO, University of Trento, Italy
Riccardo Vanini, PhD student in Biomolecular Sciences, Department CIBIO, University of Trento, Italy

*Workshop participants are required to bring a laptop with an installed web browser.

**Limited spots available and subject to pre-registration

WELCOME ADDRESS FROM THE COMMITTEE
Plenary Hall (Amphitheatеr)

OPENING KEYNOTE LECTURE
Plenary Hall (Amphitheatеr)

Chair: Michael Silverman, Children`s Hospital of Philadelphia, USA 

A seeding reaction to colonizing microbes early in life
Petter Brodin, Imperial College London, UK

SESSION 1 – THE MICROBIOME FROM PREGNANCY TO EARLY LIFE – PART 1
Plenary Hall (Amphitheatеr)

Chair: AlexandraZhernakova, University Medical Center Groningen, The Netherlands 

14:45 15:00 
The gut microbiome in the first 1000 days of life 
Omry Koren, Bar-Ilan University, Israel

15:0015:15
Leveraging early-life microbes to prevent autoimmune diabetes
Michael Silverman, Children’s Hospital of Philadelphia, USA

15:15 – 15:25
Mom Matters: Maternal influences on infant gut microbiome and health in 714 mother-infant pairs in the Lifelines NEXT cohort
T
rishla Sinha, University of Groningen, The Netherlands

15:25 – 15:50
Panel Discussion

COFFEE BREAK, POSTER VIEWING, EXHIBITION AND NETWORKING
Exhibition & Networking Area (Atrium)

SESSION 2 – COMPUTATIONAL, INTEGRATIVE AND AI TOOLS FOR META-OMICS – PART 1
Plenary Hall (Amphitheatеr)

Chair: Liviana RicciCibio, University of Trento, Italy 

16:20 – 16:35
The transmission landscape of the human microbiome: a One Health perspective 
Mireia Valles Colomer, University Pompeu Fabra, Barcelona, Spain

16:35 16:50
Decoding diet-microbiome interactions using data science and ex vivo models
Mani Arumugam, University of Copenhagen, Denmark

16:50 – 17:00
Digital biology in microbiome innovation 
Henrik Bjørn Nielsen, Cmbio, Denmark 

17:00 – 17:10
Microbial virulence landscapes of the infant gut across birth modes and locations
Valeriia Ivanova, Bar Ilan University, Israel 

17:10 – 17:25
Panel Dicus
sion

SESSION 3 – MICROBIOME, AGING AND DISEASE
Plenary Hall (Amphitheatеr)

Chair: Mirjana Rajlić-StojanovićUniversity of Belgrade, Serbia

17:25  17:40 
Gut microbiome associations with diet and cardiometabolic health 
Francesco Asnicar, University of Trento, Italy

17:40  17:55
Strain- and genetic-level resolved microbial roles in human health and biological aging 

Jingyuan Fu, University of Groningen, The Netherlands

17:55 – 18:05
Meta-analysis of ischemic stroke microbiota identifies cross-cohort microbial signatures predictive of outcome
Adam Sorbie, LMU University Hospital, Germany

18:05 – 18:15
Strain-specific neuroprotection by human gut bacteria: blautia fusiformis and ruminococcoides intestinale extend lifespan and preserve cognition in C. elegans neurodegeneration models via distinct molecular programs
Stefan Jakovljevic, Institute Of Molecular Genetics And Genetic Engineering, Belgrade, Serbia

18:15 – 18:25
Full-length 16S rRNA sequencing of fecal samples reveals distinct gut microbiome signatures in Alzheimer’s and Parkinson’s disease
Simon De Jaegher, University Of Siena, Italy 

18:25 – 18:35
Age-associated remodelling of the human gut microbiome: insights from a meta-analysis of public metagenomic datasets 
Dusan Radojevic, University of Belgrade, Serbia 

18:35 – 18:45
Exploring Early Life Microbiome Signatures in a Malawian Infant Cohort  
Leon Mijic, University of Birmingham, United Kingdom

18:45 – 18:55
Deciphering gut bacteria-regulated pathways of longevity in Caenorhabditis elegans
Miroslav Dinic, University of Belgrade, Serbia  

18:55  19:15
Panel Discussion 

WELCOME RECEPTION
Exhibition & Networking Area (Atrium)

KEYNOTE LECTURE
Plenary Hall (Amphitheatеr)
Chair: Rochellys Diaz Heijtz
Karolinska Institutet, Sweden  

Gut feelings: The microbiome as a key regulator of brain & behaviour across the lifespan 
John F. Cryan, University College Cork, Ireland

SESSION 4 –THE GUT-BRAIN AXIS & THE ROLE OF GUT TESTING IN HUMAN DISORDERS 
Plenary Hall (Amphitheatеr)

Chair: John F. Cryan, University College Cork Ireland

09:00 – 09:15
Microbiota-derived peptidoglycan signaling shapes brain development and behavior  
Rochellys Diaz Heijtz, Karolinska Institutet, Sweden  

09:15 – 09:30
The gut microbiome for prediction of disease development or drug response
Rinse Weersma
, University of Groningen, The Netherlands

09:30 – 09:45
Potential Uses of Gut Microbiome Testing
Tim Spector, King`s College London, UK

09:45 – 09:55
Gut microbiota in children with neurodevelopmental disorders  
Ekaterina Voroshilina, DNA – Technology 

09:55 – 10:15
Panel Discussion

COFFEE BREAK, POSTER VIEWING, EXHIBITION AND NETWORKING
Exhibition & Networking Area (Atrium)

SESSION 5 – MICROBIOMES BEYOND BACTERIA
Plenary Hall (Amphitheatеr)

Chair: Alexandra Zhernakova, University Medical Center Groningen, The Netherlands  

10:45 – 11:00
We need to talk …. about the virome 

Collin Hill, University College Cork, Ireland

11:00 – 11:10
Maternal gut mycobiota-derived fungal extracellular vesicles in fetal environment 
Anna Kaisanlahti, University of Oulu, Finland

11:10 – 11:20
A five-year longitudinal study reveals population-dependent phage dynamics and high turnover rates in the human gut  
Yishay Pinto, Bar-Ilan University, Israel

11:20 – 11:35
Panel Discussion

INDUSTRY SESSION BY DNA-TECHNOLOGY
Plenary Hall (Amphitheatеr)

Chair: Alexandra Zhernakova, University Medical Center Groningen, The Netherlands 

How Molecular Testing Can Improve Vaginal Microbiome Evaluation in Women’s Health
Ekaterina Voroshilina
DNA – Technology 

LUNCH BREAK, POSTER VIEWING, EXHIBITION AND NETWORKING
Exhibition & Networking Area (Atrium)

SESSION 6 – THE MICROBIOME FOR CLINICIANS: HOW TO MOVE MICROBIOME INTO CLINICAL PRACTICE – PART 1
Plenary Hall (Amphitheatеr)

Chair: Gianluca Ianiro, Universita Catollica del Sacro Cuore in Rome, Italy 

13:30 – 13:45
The opportunities of exploiting gut microbiome in clinical practice 
Gianluca Ianiro, Universita Catollica del Sacro Cuore in Rome, Italy

13:45 – 14:00 
Gut microbes as medicine? From preclinical mechanisms to clinical application
Patrice Cani, University of Louvain, Brussels, Belgium

14:00 – 14:10
Bloating and microbiota: therapeutic options
Dan L. Dumitrașcu, Iuliu Hațieganu University of Medicine and Pharmacy, Romania  

14:10 – 14:20 
Influence of nutrition to gut microbiome and gastrointestinal and liver diseases 
Vladimir Milivojevic, School of Medicine, Belgrade University, Serbia 

14:20 – 14:30
Turku clinical microbiome bank, TCMB  
Eveliina Munukka, Turku University Hospital, Finland 

14:30 – 14:40
Evolution of the peri-implant microbiome and its relationship with long-term marginal bone stability: A randomized clinical study 
Pablo Galindo-Moreno, University of Granada, Spain

14:40 – 14:50
Modulating the microbiota: a systematic review of probiotics as adjunctive therapy for gastroesophageal reflux disease 
Abdulrahman Ismaiel, University of Medicine and Pharmacy, Cluj-Napoca, Romania 

14:50  15:00
Standardized probiotic supplementation shows favourable trends in reducing Incidence of necrotizing enterocolitis and mortality in very preterm infants: a retrospective cohort study 
Marijana Vidmar Šimic, University Medical Centre Ljubljana, Slovenia 

15:00 – 15:30
Panel Discussion

COFFEE BREAK, POSTER VIEWING, EXHIBITION AND NETWORKING
Exhibition & Networking Area (Atrium)

SESSION 7 – MICROBIOME FROM PREGNANCY TO EARLY LIFE – PART 2
Plenary Hall (Amphitheatеr)

Chair: Michael Silverman, Children`s Hospital of Philadelphia, USA 

16:1016:25
Are we missing half of the picture? The early life virome
Alexandra Zhernakova,
University Medical Center Groningen, The Netherlands

16:25 – 16:35
Early-life exposures and functional maturation trajectories of the infant gut microbiome: Insights from a longitudinal meta-analysis  
Maxime Naour, Nantes Université, France 

16:35 – 16:45 
Gut Plasmidome Composition and Plasmid-Encoded Gene Functions During Pregnancy and the Postpartum Period in Mothers From the Lifelines NEXT Cohort
Sergio George, University of Groningen, The Netherlands

16:45 – 16:55
Microbial strain transmission between infants in the nursery drives gut microbiome development
Liviana Ricci, Cibio, University of Trento, Italy

16:55 – 17:10 
Panel Discussion

SESSION 8 – OTHER MICROBIOMES IN HEALTH AND DISEASE (VAGINAL, ORAL, SKIN, ETC.)
Plenary Hall (Amphitheatеr)

Chair: Patrice Cani, UCLouvain, Belgium

17:10 – 17:25
The Dynamic Vaginal Microbiome: Cycles, Pregnancy, and Microbial Transmission to the Next Generation.  
Ina Schuppe Koistinen, Karolinska Institutet, Sweden

17:25 – 17:35
Changes in the oral microbiome and systemic inflammatory biomarkers one year after periodontal therapy: bergen oral intervention study 
Randi J Bertelsen, Oral Health Center of Expertise in Western Norway, Norway

17:35 – 17:45 
Integrated salivary microbiome and proteome profiling uncovers functional diversity linked to obesity among Qataris 
Selvasankar Murugesan, Reproductive and Perinatal Health Division, Sidra Medicine, Doha, Qatar 

17:45 – 18:00 
Panel Discussion

SESSION 9 – MICROBIOME FROM PREGNANCY TO EARLY LIFE – PART 3
Plenary Hall (Amphitheatеr)

Chair: Nicola Segata, University of Trento, Italy   

08:30  08:45
Maternally derived microbial metabolites and the fetal immune system 
Liza Konnikova, Yale University School of Medicine, USA

08:45– 09:00
What Shapes the Early-Life Microbiota, Resistome and Phageome?: Insights from MAMI cohort
Maria Carmen Collado, Institute of Agrochemistry and Food Technology-National Research Council (IATA-CSIC), Spain  

09:00 – 09:20
Panel discussion

SESSION 10 – THE HUMAN MICROBIOME AND CANCER
Plenary Hall (Amphitheatеr)

Chair: Dino TarabarUniversity Hospital Center Dr Dragiša Mišović, Serbia 

09:20 – 09:32
Gut microbiota mediates the impact of oral iron therapy on colorectal cancer progression in ApcMin/+ mice  
Manuela M Santos, CRCHUM Montréal, Canada 

09:32 – 09:44 
Anastomotic response microbial subtypes (ARMS) predict anastomotic leakage after colorectal cancer surgery
Jonge Wouter, University of Amsterdam, The Netherlands

09:44 – 10:00 
Panel Discussion  

COFFEE BREAK, POSTER VIEWING, EXHIBTION AND NETWORKING 
Exhibition & Networking Area (Atrium) 

SESSION 11 – THE MICROBIOME FOR CLINICIANS: HOW TO MOVE MICROBIOME INTO CLINICAL PRACTICE – PART 2
Plenary Hall (Amphitheatеr)

Chair: Miodrag KrsticUniversity of Belgrade, Serbia 

10:40 –10:52 
Gut microbiota in endometriosis – screening or treatment?  
Elvira Brătilă, Alexandra Bausic, Carol Davila University of Medicine and Pharmacy, Romania

10:52 –11:04 
Microbiome and obesity: the hidden connection
Gerasim Temelkov, Director of a private gastroenterology and longevity practice, Bulgaria

11:04 –11:16
Oral administration of Lactobacillus crispatus in pregnant women colonized with GBS: preliminary results 
Radu Vlădăreanu, Mihaela Boț, Carol Davila University of Medicine and Pharmacy, Romania

11:16 – 11:28
When hormones meet the microbiome…
Dejana Milojević, 
MediGroup, Serbia

11:28 – 11:40
Fertility, Pregnancy, Obesity: One Axis, One Microbiome
Desimira Mironova, Bulgarian Association of reproductive and metabolic disease, Bulgaria

11:40 –12:00
Panel Discussion

SESSION 12 –THE MICROBIOME, THE IMMUNE SYSTEM AND THERAPEUTICS
Plenary Hall (Amphitheatеr)

Chair: Liza Konnikova, Yale University School of Medicine, USA 

12:00 – 12:10
Beyond the Drug: The “Mediterranean Code”—Microbiome, Immunity, and Clinical translation
Nitida Pastor Perez, Mead Johnson Nutrition, Spain

12:10 – 12:20 
Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis 
Nissan Yissachar, Bar-ilan University, Israel

12:20 – 12:30
Opsonisation of vaginal microbiota in women at high-risk of delivering preterm  
Belen Gimeno Molina, Imperial College London, United Kingdom 

12:30 – 12:40
Aggression: a gut reaction? The cross-generational effects of gut microbiome manipulation on aggression  
Sondra Turjeman, Bar-Ilan University, Isreal 

12:40 – 13:00 
Panel discussion  

LUNCH BREAK, POSTER VIEWING, EXHIBITION AND NETWORKING
Exhibition & Networking Area (Atrium)

SESSION 13 – COMPUTATIONAL, INTEGRATIVE AND AI TOOLS FOR META-OMICS – PART 2
Plenary Hall (Amphitheatеr)

Chair: Francesco Asnicar, University of Trento, Italy  

14:00 – 14:10
Unravelling the role of gut microbial proteases genes in inflammatory bowel disease: a cross-species metagenomic study 
Riccardo Vanini, CIBIO, University of Trento, Italy 

14:10 – 14:20
Unravelling the BGC-ome of the human gut prokaryome: a comprehensive mining of biosynthetic gene clusters in a northern Netherlands human cohort 
Cristian D Grisales-Vargas, University Medical Center Groningen, The Netherlands 

14:20 – 14:30
Translating microbiome research into clinical decision support 
Mattia BolzanPreBiomics, Italy 

14:30 – 14:45 
Panel discussion  

KEYNOTE LECTURE
Plenary Hall (Amphitheatеr)

Chair: Liza KonnikovaYale University School of Medicine, USA 

Human-to-human microbiome transmission: from research to clinical applications
Nicola Segata, University of Trento, Italy

CLOSING DISCUSSION WITH THE COMMITTEE 
Plenary Hall (Amphitheatеr)